Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA

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SRP052620

Homo sapiens

12 Downloadable Samples

Illumina HiSeq 2500

Submitter Supplied Information

Description

To determine the global effects of ASCT2 inhibition, we used next generation sequencing to determine mRNA expression changes in PC-3 cells treated with BenSer or GPNA for 48 h. Overall design: Examination of two different ASCT2 inhibitors BenSer and GPNA in prostate cancer cell line PC-3.

PubMed ID

25693838

Publication Title

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development.

Total Samples

Submitter’s Institution

No associated institution

Authors

Wang Q, Hardie RA, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Nagarajah R, Wong JJ, Metierre C, Pinello N, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JE, Holst J

Source Repository

Sequence Read Archive (SRA)

No rows found