Expression data from UMUC3 cells transduced with non-targeted shRNA and shRNA specific to AGL

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GSE73456

Homo sapiens

4 Downloadable Samples

Affymetrix Human Genome U219 Array (hgu219)

Submitter Supplied Information

Description

Loss of Amylo-alpha-1-6-glucosidase-4-alpha-glucanotransferase (AGL) drives bladder cancer growth. Low AGL expression predicts poor patient outcome. Currently no specific therapeutically tractable targets/pathways exist that could be used to treat patients with low AGL expressing bladder tumors.

PubMed ID

26490312

Publication Title

Loss of Glycogen Debranching Enzyme AGL Drives Bladder Tumor Growth via Induction of Hyaluronic Acid Synthesis.

Total Samples

Submitter’s Institution

BioMarin Pharmaceutical Inc.

Authors

Guin S, Ru Y, Agarwal N, Lew CR, Owens C, Comi GP, Theodorescu D

Source Repository

Gene Expression Omnibus (GEO)

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