Gene expression profiles of tumor-induced pTregs and anergic tumor-specific CD4+ T cells

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GSE113624

Mus musculus

30 Downloadable Samples

Affymetrix Mouse Gene 2.1 ST Array (mogene21st)

Submitter Supplied Information

Description

Up to now the role of tumor-specific pTregs and anergic cells during tumor development is not fully understood. Here we used a genetically-induced tumor expressing a MHC-II restricted DBY model antigen to characterize the tumor-induced pTregs and anergic cells that arise early during tumor development.

PubMed ID

29844317

Publication Title

Induction of anergic or regulatory tumor-specific CD4<sup>+</sup> T cells in the tumor-draining lymph node.

Total Samples

Submitter’s Institution

Curie Institute

Authors

Alonso R, Flament H, Lemoine S, Sedlik C, Bottasso E, Péguillet I, Prémel V, Denizeau J, Salou M, Darbois A, Núñez NG, Salomon B, Gross D, Piaggio E, Lantz O

Source Repository

Gene Expression Omnibus (GEO)

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